Invisible Illness: Periodic Fever Syndrome
Periodic fever syndrome does not refer to a single disease, nor is it a specific diagnosis, but rather a general term, a classification of a group of diseases. The term “periodic fever syndrome” refers to several different autoinflammatory diseases that have similar symptoms–the primary symptom being a recurrent fever for which no infectious cause can be found. The patient just keeps getting fevers, often accompanied by a range of other symptoms. These are primarily genetic conditions and are not contagious. Autoinflammatory diseases are caused by a malfunction in the innate immune system.
Common Periodic Fever Syndrome Symptoms:
Fever (recurrent, and accompanied by some of the following symptoms)
Swollen lymph nodes
Joint pains, or arthritis Fatigue
Abnormal blood test results during flares of symptoms, including: high white blood count (WBC) and high inflammatory markers CRP and ESR
Serositis (pericarditis, pleurisy)